As fossil fuels dwindle, the future demands a switch to renewable energy. In this regard, the valorization of plant oils and waste streams from their production as feedstocks for biofuels¹, bioplastics², and fine chemicals³ has gained significant attention recently. When this approach is coupled to chemo-catalysis in combination with enzymatic reactions, it provides a highly effective tool for lipid transformation into high-value-added chemicals⁴. Upon many enzymes, the application of lyases, particularly hydratases and decarboxylases, in lipid-based cascades is of interest. Hydratases allow the hydroxyfunctionalization of unsaturated fatty acids, while decarboxylases remove the carboxyl groups. This work will present their application in chemo-enzymatic cascades, covering recent advancements in producing novel hydroxy fatty acids and bio-based hydrocarbons.
BIO-001: Application of Lyases for Chemo-enzymatic Cascade Reactions for the Biotechnological Utilization of Lipids
