PHCO-002: Self-shaping as a Route for Control of Drop Size and Dispersions Rheology

The design of disperse systems with controlled drop size, morphology, and rheology is crucial in the production of foods, cosmetics, and pharmaceuticals with desired characteristics. A particularly promising route involves the spontaneous self-shaping of droplets, first described in detail by Denkov et al. [1, 2], which enables the formation of lipid particles with regular, non-spherical shapes. Building on this foundation, we present an efficient self-emulsification procedure based on one or more freeze–thaw cycles of predispersed lipid droplets in a coarse oil-in-water emulsion. During these thermal cycles, the frozen droplets spontaneously burst into hundreds or thousands of smaller droplets without the need for mechanical agitation [3]. The resulting non-spherical droplet morphologies significantly influence dispersion rheology: gel-like, non-flowing systems can be obtained even at low oil volume fractions when the emulsions polydisperse droplets. Furthermore, we demonstrate that the optimal drop size range is d32 ≈ 4-13 μm for achieving such rheological behaviour. The obtained results are explained through a mechanistic framework, and guiding principles are provided for preparing emulsions with increased viscosities using this new approach. [4]

Figure 1. The presented figure illustrates: yield stress of O/W emulsions stabilized by non-ionic surfactants as a function of the oil concentration, picture of a bulk sample stored at 5°C and microscopy image showing non-spherical frozen particles present in sample with 11 vol. % oil at 5°C. Scale bar = 10 μm.

References
[1] N. Denkov et al., Nature, 2015, 528, 392-395, doi: 10.1038/nature16189.
[2] D. Cholakova et al., ACIS, 2016, 235, 90 – 107, doi: 10.1016/j.cis.2016.06.002
[3] S. Tcholakova et al., Nature Com., 2017, 8, 15012, doi: 10.1038/ncomms15012
[4] Z. Valkova et al., Colloid Surf. A, 2025, doi: 10.1016/j.colsurfa.2025.136284

Acknowledgements: The study was funded by Bulgarian Ministry of Edication and Science, under the National Reseearch Program “VIHREN”, project ROTA-Active (no. KP-06-DV-4/16.12.2019).

Euro Fed Lipid e.V.
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